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Tempol-d17,15N

CAT: 0804-HY-100561S-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-100561S-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Tempol-d17,15N is the deuterium labeled Tempol[1]. Tempol is a general superoxide dismutase (SOD) -mimetic agent that efficiently neutralizes reactive oxygen species (ROS) [2][3].
CAS Number
90429-66-6
Product Name Alternative
4-Hydroxy-TEMPO-d17,15N
UNSPSC
12352005
Target
Autophagy; Reactive Oxygen Species (ROS)
Type
Isotope-Labeled Compounds
Related Pathways
Autophagy; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
98.44
Solubility
10 mM in DMSO
Smiles
[O][15N](C(C([2H])([2H])[2H])(C1([2H])[2H])C([2H])([2H])[2H])C(C([2H])([2H])[2H])(C([2H])([2H])C1([2H])O)C([2H])([2H])[2H]
Molecular Formula
C9HD17 15NO2
Molecular Weight
190.34
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Vilar-Pereira G, et al. Resveratrol Reverses Functional Chagas Heart Disease in Mice. PLoS Pathog. 2016 Oct 27;12 (10) :e1005947.|[3]Chatterjee PK, et al. Tempol, a membrane-permeable radical scavenger, reduces oxidant stress-mediated renal dysfunction and injury in the rat. Kidney Int. 2000 Aug58 (2) :658-73.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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Alternative Products

CatalogName
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