Tempol-d17,15N

CAT: 0804-HY-100561S-01Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0804-HY-100561S-01Size:1 mg

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Description

Tempol-d17,15N is the deuterium labeled Tempol[1]. Tempol is a general superoxide dismutase (SOD) -mimetic agent that efficiently neutralizes reactive oxygen species (ROS) [2][3].

CAS Number

90429-66-6

Product Name Alternative

4-Hydroxy-TEMPO-d17,15N

UNSPSC

12352005

Target

Autophagy; Reactive Oxygen Species (ROS)

Type

Isotope-Labeled Compounds

Related Pathways

Autophagy; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

Cancer-programmed cell death

Field of Research

Cancer

Purity

98.44

Solubility

10 mM in DMSO

Smiles

[O][15N](C(C([2H])([2H])[2H])(C1([2H])[2H])C([2H])([2H])[2H])C(C([2H])([2H])[2H])(C([2H])([2H])C1([2H])O)C([2H])([2H])[2H]

Molecular Formula

C9HD17 15NO2

Molecular Weight

190.34

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Vilar-Pereira G, et al. Resveratrol Reverses Functional Chagas Heart Disease in Mice. PLoS Pathog. 2016 Oct 27;12 (10) :e1005947.|[3]Chatterjee PK, et al. Tempol, a membrane-permeable radical scavenger, reduces oxidant stress-mediated renal dysfunction and injury in the rat. Kidney Int. 2000 Aug58 (2) :658-73.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Chemical Information

4-Hydroxy-2,2,6,6-tetramethylpiperidine-D17-1-15N-1-oxyl

CAS Number	90429-66-6
PubChem CID	168476662
IUPAC Name	3,3,4,5,5-pentadeuterio-1-hydroxy-2,2,6,6-tetrakis(trideuteriomethyl)(115N)azinan-4-ol
Molecular Formula	C9H19NO2
Molecular Weight	191.35
XLogP	0.9
Topological Polar Surface Area	43.7
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	0
Heavy Atom Count	12
Formal Charge	0
Complexity	159

SMILES

[2H]C1(C(C(C([15N](C1(C([2H])([2H])[2H])C([2H])([2H])[2H])O)(C([2H])([2H])[2H])C([2H])([2H])[2H])([2H])[2H])([2H])O)[2H]

InChI

InChI=1S/C9H19NO2/c1-8(2)5-7(11)6-9(3,4)10(8)12/h7,11-12H,5-6H2,1-4H3/i1D3,2D3,3D3,4D3,5D2,6D2,7D,10+1

InChIKey

CSGAUKGQUCHWDP-BIXFOSJQSA-N

Chemical Structure

2D Structure

CAS: 90429-66-6

CID: 168476662

Formula: C9H19NO2

MW: 191.35

Interactive 3D Structure

Loading 3D structure...

View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	191.35
XLogP3	0.9
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	0
Exact Mass	191.245318424
Monoisotopic Mass	191.245318424
Topological Polar Surface Area	43.7 Å²
Heavy Atom Count	12
Formal Charge	0
Complexity	159
Isotope Atom Count	18
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Related Products

Catalog	Name
HY-100561S1-01	Tempol-d17
HY-W002004S-01	4-Amino-TEMPO-d17,15N
HY-100561-01	Tempol
HY-100561R-01	Tempol (Standard)
HY-W002004S1-01	4-Amino-TEMPO-d17
HY-129242S-01	Tempone-15N, d16
HY-B0649S-01	Propofol-d17
HY-N1131S	Triacetonamine-d17
HY-132413S	Octhilinone-d17
HY-W706234	Nonanoyl-CoA-d17

Alternative Products

Catalog	Name
B2046-S	Tempol

Tempol-d17,15N

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