Dimemorfan (phosphate)

CAT: 0804-HY-B2215-01Size: 50 mgDry Ice: NoHazardous: No

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CAT#:0804-HY-B2215-01Size:50 mg

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Description

Dimemorfan phosphate is a sigma 1 receptor agonist, used as a potent antitussive.

CAS Number

36304-84-4

UNSPSC

12352005

Target

Sigma Receptor

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Dimemorfan_phosphate.html

Purity

99.94

Solubility

DMSO : 1 mg/mL (ultrasonic) |H2O : 10 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=P(O)(O)O.CN1[C@](CC2=CC=C(C)C=C32)([H])[C@](CCCC4)([H])[C@]34CC1

Molecular Formula

C18H28NO4P

Molecular Weight

353.39

References & Citations

[1]Shin EJ, et al. Dimemorfan prevents seizures induced by the L-type calcium channel activator BAY k-8644 in mice. Behav Brain Res. 2004 May 5;151 (1-2) :267-76.|[2]Wang YH, et al. Anti-inflammatory effects of dimemorfan on inflammatory cells and LPS-induced endotoxin shock in mice. Br J Pharmacol. 2008 Jul;154 (6) :1327-38.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Launched

Isoform

Sigma 1 Receptor

Chemical Information

Morphinan, 3,17-dimethyl-, (9alpha,13alpha,14alpha)-, phosphate (1:1)

CAS Number	36304-84-4
PubChem CID	198165
IUPAC Name	(1S,9S,10S)-4,17-dimethyl-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-triene;phosphoric acid
Molecular Formula	C18H28NO4P
Molecular Weight	353.4
Topological Polar Surface Area	81
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	0
Heavy Atom Count	24
Formal Charge	0
Complexity	401

SMILES

CC1=CC2=C(C[C@H]3[C@@H]4[C@]2(CCCC4)CCN3C)C=C1.OP(=O)(O)O

InChI

InChI=1S/C18H25N.H3O4P/c1-13-6-7-14-12-17-15-5-3-4-8-18(15,16(14)11-13)9-10-19(17)2;1-5(2,3)4/h6-7,11,15,17H,3-5,8-10,12H2,1-2H3;(H3,1,2,3,4)/t15-,17+,18+;/m1./s1

InChIKey

ODJHDWLIOUGPPA-URVXVIKDSA-N

Chemical Structure

2D Structure

CAS: 36304-84-4

CID: 198165

Formula: C18H28NO4P

MW: 353.4

Interactive 3D Structure

Loading 3D structure...

View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	353.4
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	0
Exact Mass	353.17559537
Monoisotopic Mass	353.17559537
Topological Polar Surface Area	81 Å²
Heavy Atom Count	24
Formal Charge	0
Complexity	401
Isotope Atom Count	0
Defined Atom Stereocenter Count	3
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	2
Compound Is Canonicalized	Yes

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Alternative Products

Catalog	Name
MBS5751499	Dimemorfan phosphate
RG-E140986-01	Dimemorfan
RM-D193807-01	Dimemorfan Impurity 7
RM-D193806-01	Dimemorfan Impurity 6
RM-D193808-01	Dimemorfan Impurity 8
RM-D193802-01	Dimemorfan Impurity 2
RM-D193810-01	Dimemorfan Impurity 10
RM-D193804-01	Dimemorfan Impurity 4
RM-D193803-01	Dimemorfan Impurity 3
RM-D193809-01	Dimemorfan Impurity 9

Dimemorfan (phosphate)

Chemical Information

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