Oleandomycin (phosphate)

CAT: 0804-HY-116010A-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-116010A-01Size:5 mg
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Description
Oleandomycin phosphate is a macrolide antibiotic structurally closely related to Erythromycin. Oleandomycin is similar to Erythromycin with antimicrobial activity. Oleandomycin inhibits protein synthesis by interference with translation of activated amino acids to nascent peptide chains on the ribosomes[1][2].
CAS Number
[7060-74-4]
UNSPSC
12352005
Hazard Statement
H301-H312-H330-H410
Target
Antibiotic; Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/oleandomycin-phosphate.html
Smiles
O=C1[C@H](C)[C@@H](O)[C@@H](C)[C@@H](C)OC([C@H](C)[C@@H](O[C@]2([H])O[C@@H](C)[C@H](O)[C@@H](OC)C2)[C@H](C)[C@@H](O[C@@]3([H])[C@H](O)[C@@H](N(C)C)C[C@@H](C)O3)[C@@H](C)C[C@@]14CO4)=O.OP(O)(O)=O
Molecular Formula
C35H64NO16P
Molecular Weight
785.85
Precautions
P264-P270-P330-P405-P501
References & Citations
[1]Vilches C, et al., Role of glycosylation and deglycosylation in biosynthesis of and resistance to oleandomycin in the producer organism, Streptomyces antibioticus. J Bacteriol. 1992 Jan;174 (1) :161-5.|[2]Semenitz E, et al. The antibacterial activity of oleandomycin and erythromycin--a comparative investigation using microcalorimetry and MIC determination. J Antimicrob Chemother. 1978 Sep;4 (5) :455-7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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