ATG-031

CAT: 0804-HY-P99176-01Size: 1 mgDry Ice: YesHazardous: No
CAT#:0804-HY-P99176-01Size:1 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
ATG-031 is a humanized anti-CD24 monoclonal antibody with high affinity and specificity. ATG-031 interacts with Siglec-10 expressed by tumor-associated macrophages. ATG-031 effectively stimulates macrophage-mediated phagocytosis and induces cancer cell destruction by blocking the anti-phagocytic surface proteins. ATG-031 can be used in the study of haematological malignancies as well as solid tumors. Recommend Isotype Controls: Human IgG4 (S228P) kappa, Isotype Control (HY-P99003) [1][2][3].
UNSPSC
12352203
Target
Others
Type
Inhibitory Antibodies
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/atg-031.html
Purity
99
Solubility
10 mM in DMSO
Smiles
[ATG-031]
Molecular Weight
(146.305 kDa)
References & Citations
[1]Peng Chen, et al., (2022) . ATG-031, a first-in-class anti-CD24 antibody, showed potent preclinical anti-tumor efficacy by blocking “don’t-eat-me” signal. Journal for ImmunoTherapy of Cancer 2022.|[2]Peng Chen, et al., Abstract 6641: ATG-031, a first-in-class humanized anti-CD24 antibody, demonstrates potent in vivo efficacy and repolarizes tumor-associated macrophages in the TME. Cancer Res 1 April 2023; 83 (7_Supplement) : 6641.|[3]Chen P, et al., 1337 The preclinical characterization and translational research of ATG-031, a first-in-class humanized anti-CD24 antibody, for the treatment of solid tumors and hematological malignanciesJournal for ImmunoTherapy of Cancer 2023;11
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
Phase 1

Related Products

CatalogName
HY-163782-01SMIP-031
HY-P990581ELB-031
HY-179256U-031
HY-P991306ATG-032
HY-122849CHMFL-KIT-031
HY-139081-01GDC-0310
HY-138170-01ALC-0315
HY-176198BI-0319
HY-138170AALC-0315 (Excipient)
HY-172329Q1-ALC-0315 (iodide)

Alternative Products

CatalogName
T78277ATG-031
HB630016-01Research Grade Anti-Human CD24 (ATG 031)
A135839Anti-CD24 (ATG 031) Biosimilar (Monoclonal, IgG)
T9901A-1015-01ATG-032
YP-W79766-01Human ATG-P62 (ATG-P62) ELISA Kit
MBS5773239ML-031
TP2528-01ACE-031
T9901A-1681-01EBI-031
C13608-01AZD0364 (ATG-017)
F46220-0.08MLATG-5 Antibody

Popular Products