Products for Research Use Only
RegisterLogin

RN-1665

CAT: 0804-HY-160900-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-160900-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
RN-1665 is an orally active TRPV4 antagonist that exhibits excellent selectivity for related TRP receptors such as TRPV1, TRPV3 and TRPM8. RN-1665 is a TRPV4 probe for focus screens, with IC50s of 0.26 μM and 0.39 μM for hTRPV4 and rTRPV4 from human and rat, respectively[1].
CAS Number
1803003-65-7
UNSPSC
12352005
Target
TRP Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/rn-1665.html
Purity
99.93
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=C(S(F)(F)(F)(F)F)C=C1)NC2=CC=C(S(=O)(N3CCN(C(C)C)CC3)=O)C=C2
Molecular Formula
C20H24F5N3O3S2
Molecular Weight
513.54
References & Citations
[1]Wei ZL, et al. Identification of orally-bioavailable antagonists of the TRPV4 ion-channel. Bioorg Med Chem Lett. 2015 Sep 15;25 (18) :4011-5.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
TRPV4

Related Products

CatalogName
HY-19976-01RN-1747
HY-19975-01RN-1734
HY-110270-01RN-9893
HY-102014-01RN-18
HY-110270ARN-9893 (hydrochloride)
HY-110130-01RN-1 (dihydrochloride)
HY-170799HNC-1664
HY-105330SIB 1663
HY-150726-01ODN 1668
HY-172737-01RP-1664

Alternative Products

CatalogName
MBS5819419RN-1665
BA7053-5RN-9893
BA1946-50RN-18
B7493-10RN 1734
B7492-10RN 1747
MBS5758461RN-1734
GTR19174209-01RN-1747

Popular Products