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RN-1747

CAT: 0013-GTR19174209-01Size: 1 ml x 10 mM (in DMSO)Dry Ice: NoHazardous: No
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CAT#:0013-GTR19174209-01Size:1 ml x 10 mM (in DMSO)
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
RN-1747 is a selective TRPV4 channel agonist with EC50 values of 0.77 μM (human), 4.0 μM (mouse), and 4.1 μM (rat), and also acts as a TRPM8 antagonist (IC50: 4 μM) . This compound is a valuable research tool for investigating TRP channel physiology in models of pain, osmoregulation, and respiratory function in both cellular and animal studies.
CAS Number
1024448-59-6
Product Name Alternative
RTRPV4, RN1747, RN-1747, RN 1747, TRP Channel, TRPChannel, TRPV Channel, TRPM8, TRPVChannel, Transient receptor potential channels, mTRPV4, inhibit, hTRPV4, Inhibitor
Field of Research
Pharmacology & Drug Discovery
Purity
99.29% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.05 mM) ; DMSO:55 mg/mL (138.94 mM)
Smiles
[O-][N+] (=O) C1=C (C=CC (Cl) =C1) S (=O) (=O) N1CCN (CC2=CC=CC=C2) CC1
Molecular Formula
C17H18ClN3O4S
Molecular Weight
395.86
Storage Conditions
-20°C
Notes
For research use only.

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