SIB 1663

• Description :

  SIB 1663 is a conformationally restricted analog of nicotine. SIB-1663 selectively activatedα2β4 and α4β4 human recombinant neuronal nAChRs. SIB 1663 can increase DA and NE release. SIB 1663 can be used for the research of neurological disease[1].

• UNSPSC :

  12352005

• Target :

  NAChR

• Related Pathways :

  Membrane Transporter/Ion Channel; Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Smiles :

  COC1=NC=C2C(CCC3CCNC23)=C1

• Molecular Formula :

  C12H16N2O

• Molecular Weight :

  204.27

• References & Citations :

  [1]Rao TS, et al. Pharmacological characterization of SIB-1663, a conformationally rigid analog of nicotine. Brain Res. 2004 Apr 2;1003 (1-2) :42-53.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [179064-11-0]