Products for Research Use Only
RegisterLogin

SIB 1663

CAT: 0804-HY-105330Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-105330Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
SIB 1663 is a conformationally restricted analog of nicotine. SIB-1663 selectively activatedα2β4 and α4β4 human recombinant neuronal nAChRs. SIB 1663 can increase DA and NE release. SIB 1663 can be used for the research of neurological disease[1].
CAS Number
179064-11-0
UNSPSC
12352005
Target
NAChR
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Smiles
COC1=NC=C2C(CCC3CCNC23)=C1
Molecular Formula
C12H16N2O
Molecular Weight
204.27
References & Citations
[1]Rao TS, et al. Pharmacological characterization of SIB-1663, a conformationally rigid analog of nicotine. Brain Res. 2004 Apr 2;1003 (1-2) :42-53.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Chemical Information

7-Methoxy-2,3,3a,4,5,9b-hexahydro-1H-pyrrolo[3,2-h]isoquinoline
CAS Number179064-11-0
PubChem CID10219887
IUPAC Name7-methoxy-2,3,3a,4,5,9b-hexahydro-1H-pyrrolo[3,2-h]isoquinoline
Molecular FormulaC12H16N2O
Molecular Weight204.27
XLogP1.3
Topological Polar Surface Area34.2
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count3
Rotatable Bond Count1
Heavy Atom Count15
Formal Charge0
Complexity234
SMILES
COC1=NC=C2C3C(CCC2=C1)CCN3
InChI
InChI=1S/C12H16N2O/c1-15-11-6-9-3-2-8-4-5-13-12(8)10(9)7-14-11/h6-8,12-13H,2-5H2,1H3
InChIKey
PXBSPNGMNRTLCH-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 7-Methoxy-2,3,3a,4,5,9b-hexahydro-1H-pyrrolo[3,2-h]isoquinoline
CAS: 179064-11-0
CID: 10219887
Formula: C12H16N2O
MW: 204.27
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight204.27
XLogP31.3
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count3
Rotatable Bond Count1
Exact Mass204.126263138
Monoisotopic Mass204.126263138
Topological Polar Surface Area34.2 Ų
Heavy Atom Count15
Formal Charge0
Complexity234
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count2
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
HY-102095-01SIB-1757
HY-129513SIB-1893
HY-107681SIB-1508Y
HY-107676-01SIB-1553A
HY-107676A-01SIB-1553A (free base)
HY-102094-01(E/Z) -SIB-1893
HY-18684-01SIBA
HY-19042-01YM-16638
HY-170799HNC-1664
HY-150726-01ODN 1668

Alternative Products

CatalogName
MBS5774318-01O-1663
MBS5778169R-1663
GTR19273474-01SIB 1663
S0B1085-01FTO Recombinant Rabbit mAb (S-1663-48)
NBP3-13898-20ugMouse Monoclonal VEGFR1/R2/R3 Antibody (FLT1/1663)
TL313525VDDX11 Human shRNA Lentiviral Particle (Locus ID 1663)
TL313525DDX11 Human shRNA Plasmid Kit (Locus ID 1663)
SR301177DDX11 Human siRNA Oligo Duplex (Locus ID 1663)
NBP3-14285FMouse Monoclonal VEGFR1/R2/R3 Antibody (FLT1/1663) [FITC]
NBP3-14285HMouse Monoclonal VEGFR1/R2/R3 Antibody (FLT1/1663) [HRP]

Popular Products