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Org 43553

CAT: 0804-HY-19464-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-19464-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Org 43553 is an orally active and low molecular weight (LMW) luteinizing hormone receptor (LH-R) agonist. Org 43553 shows agonistic activity to human LH and FSH receptors with EC50 values of 3.7 and 110 nM, respectively. Org 43553 can be used for the research of endocrine[1].
CAS Number
501444-88-8
UNSPSC
12352005
Target
Estrogen Receptor/ERR; GnRH Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/org-43553.html
Purity
99.30
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=C(N)C2=C(C3=CC=CC(NC(CN4CCOCC4)=O)=C3)N=C(SC)N=C2S1)NC(C)(C)C
Molecular Formula
C24H30N6O3S2
Molecular Weight
514.66
References & Citations
[1]van de Lagemaat R, et al. Induction of ovulation by a potent, orally active, low molecular weight agonist (Org 43553) of the luteinizing hormone receptor. Hum Reprod. 2009 Mar;24 (3) :640-8.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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