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Iminostilbene-d10

CAT: 0804-HY-W753956Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-W753956Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Iminostilbene-d10 is the deuterium labeled Iminostilbene. Iminostilbene is a chemical precursor of carbamazepine. Additionally, Iminostilbene is an orally active inhibitor of PKM2 (Pyruvate Kinase M2) and COX2 (Cyclooxygenase-2). Iminostilbene exerts its effects by inhibiting PKM2 and its interaction with HIF-1α and STAT3, reducing COX2 and iNOS expression, and decreasing LPS-induced release of IL-1β, IL-6, TNF-α, and MCP-1, thereby suppressing macrophage-mediated inflammatory responses and improving myocardial ischemia/reperfusion (MI/R) injury. Iminostilbene holds promise for research in inflammation regulation, cardiovascular diseases (such as MI/R injury), and macrophage-mediated immune-related diseases[1][2].
CAS Number
3044090-39-0
UNSPSC
12352005
Target
COX; HIF/HIF Prolyl-Hydroxylase; Interleukin Related; Isotope-Labeled Compounds; NO Synthase; Pyruvate Kinase; STAT; TNF Receptor
Related Pathways
Apoptosis; Immunology/Inflammation; JAK/STAT Signaling; Metabolic Enzyme/Protease; Others; Stem Cell/Wnt
Field of Research
Inflammation/Immunology
Smiles
[2H]C1=C(C2=C(NC3=C1C([2H])=C(C([2H])=C3[2H])[2H])C([2H])=C([2H])C([2H])=C2[2H])[2H]
Molecular Formula
C14HD10N
Molecular Weight
203.31
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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