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TDHL-d10

CAT: 0804-HY-W744750Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-W744750Size:1 Each
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Description
TDHL-d10 (Tergurid-d10; Terguride-d10; trans-Dihydrolisuride-d10) is the deuterium labeled TDHL (HY-12714) . TDHL (Tergurid) is a dopamine receptor agonist with a Kd of 0.39 nM for D2 receptor and an orally available 5-HT-2 receptor antagonist.
Product Name Alternative
Tergurid-d10; Terguride-d10; trans-Dihydrolisuride-d10
UNSPSC
12352005
Target
5-HT Receptor; Dopamine Receptor; Isotope-Labeled Compounds
Related Pathways
GPCR/G Protein; Neuronal Signaling; Others
Field of Research
Neurological Disease
Smiles
O=C(N[C@@H]1CN([C@]([H])(CC2=CNC3=C2C4=CC=C3)[C@@]4(C1)[H])C)N(C([2H])(C([2H])([2H])[2H])[2H])C([2H])(C([2H])([2H])[2H])[2H]
Molecular Formula
C20H18D10N4O
Molecular Weight
350.52
References & Citations
[1]Kekewska A, et al. Antiserotonergic properties of terguride in blood vessels, platelets, and valvular interstitial cells. J Pharmacol Exp Ther. 2012 Feb;340 (2) :369-76.|[2]Mizokawa T, et al. Terguride as a new anti-hyperprolactinemic agent: characterization in rats and dogs in comparison with bromocriptine. Jpn J Pharmacol. 1993 Nov;63 (3) :269-78.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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