11-HETE

• Description:

  11-HETE (11-Hydroxy-5,8,12,14-eicosatetraenoic acid) is the activator for cytochrome P450. 11-HETE upregulates the mRNA expressions of CYP1B1, CYP1A1, CYP4A11, CYP4F11, and CYP4F2, induces cell hypertrophy in RL-14 cell, and exhibits potential to be used in cardiovascular diseases[1].

• Product Name Alternative:

  11-Hydroxy-5,8,12,14-eicosatetraenoic acid

• UNSPSC:

  12352211

• Hazard Statement:

  H302-H315-H319-H335

• Target:

  Cytochrome P450

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Cardiovascular Disease

• Smiles:

  CCCCCC=CC=CC (CC=CCC=CCCCC (=O) O) O

• Molecular Formula:

  C20H32O3

• Molecular Weight:

  320.47

• Precautions:

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

• References & Citations:

  [1]Helal SA, et al., 11-Hydroxyeicosatetraenoics induces cellular hypertrophy in an enantioselective manner. Front Pharmacol. 2024 Aug 12;15:1438567.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  73804-65-6