5-HETE

• Description:

  5-HETE ((±) -5-HETE), a fatty acid, is a oxidative derivative of Arachidonic acid. 5-HETE is a mixture of 5 (S) -HETE and 5 (R) -HETE. 5-HETE is a potent aggregating agent that induces the aggregation of neutrophils with an IC50 value of 200 nM[1].

• Product Name Alternative:

  (±) -5-HETE

• UNSPSC:

  12352211

• Target:

  Endogenous Metabolite

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/5-hete.html

• Concentration:

  312.04 μM * 1 mL in Ethanol

• Purity:

  96.8

• Solubility:

  10 mM in DMSO

• Smiles:

  CCCCC/C=C\C/C=C\C/C=C\C=C\C (O) CCCC (O) =O

• Molecular Formula:

  C20H32O3

• Molecular Weight:

  320.47

• References & Citations:

  [1]J T O'Flaherty, et al. Neutrophil-aggregating activity of monohydroxyeicosatetraenoic acids. Am J Pathol. 1981 Jul;104 (1) :55-62.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Solution, -20°C, 2 years

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  71030-39-2