5-HETE

• Description :

  5-HETE ((±) -5-HETE), a fatty acid, is a oxidative derivative of Arachidonic acid. 5-HETE is a mixture of 5 (S) -HETE and 5 (R) -HETE. 5-HETE is a potent aggregating agent that induces the aggregation of neutrophils with an IC50 value of 200 nM[1].

• Product Name Alternative :

  (±) -5-HETE

• UNSPSC :

  12352211

• Target :

  Endogenous Metabolite

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/5-hete.html

• Concentration :

  312.04 μM * 1 mL in Ethanol

• Purity :

  96.8

• Solubility :

  10 mM in DMSO

• Smiles :

  CCCCC/C=C\C/C=C\C/C=C\C=C\C(O)CCCC(O)=O

• Molecular Formula :

  C20H32O3

• Molecular Weight :

  320.47

• References & Citations :

  [1]J T O'Flaherty, et al. Neutrophil-aggregating activity of monohydroxyeicosatetraenoic acids. Am J Pathol. 1981 Jul;104 (1) :55-62.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Solution, -20°C, 2 years

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [71030-39-2]