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MAP4K4-IN-7

CAT: 0804-HY-W402208Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-W402208Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MAP4K4-IN-7 (Compound 8) is a MAP4K4 inhibitor. MAP4K4-IN-7 shows moderate inhibitory activity against TNIK, MAP4K4, and MINK1 with pIC50 values of 6.8, 6.8, and 6.7 respectively. MAP4K4-IN-7 can be used for the researches of cancer and neurological disease, such as schizophrenia[1].
CAS Number
1499162-60-5
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
MAP4K
Related Pathways
MAPK/ERK Pathway
Field of Research
Cancer; Neurological Disease
Smiles
FC1=NC=CC(C2=NC3=C(N)N=CN=C3C=C2)=C1
Molecular Formula
C12H8FN5
Molecular Weight
241.22
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Read J, et al. Tool inhibitors and assays to interrogate the biology of the TRAF2 and NCK interacting kinase. Bioorg Med Chem Lett. 2019 Aug 1;29 (15) :1962-1967.
Shipping Conditions
Room temperature
Scientific Category
Reference compound2
Clinical Information
No Development Reported
Isoform
MAP4K4/HGK; MAP4K6/MINK1; MAP4K7/TNIK

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