Products for Research Use Only
RegisterLogin

UNC8969

CAT: 0013-GTR19242446-01Size: 25 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19242446-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
UNC8969 is a potent and selective macrocyclic dual inhibitor of MERTK and AXL with low nanomolar IC50 values. It demonstrates favorable pharmacokinetics and has shown significant anti-tumor efficacy in cellular models of lung cancer, supporting its utility in oncology research for studying TAM receptor signaling in vitro and in vivo.
CAS Number
3036049-17-6
Field of Research
Signal Transduction
Smiles
CC1=CC=C (N2) C=C1OC/C=C\CNC3=NC2=C (C (N[C@@H]4CC[C@@H] (C (NCCN (CC) CC) =O) CC4) =O) C=N3
Molecular Formula
C29H41N7O3
Molecular Weight
535.68
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

(10Z)-N-[4-[2-(diethylamino)ethylcarbamoyl]cyclohexyl]-15-methyl-13-oxa-2,6,8,19-tetrazatricyclo[12.3.1.13,7]nonadeca-1(18),3(19),4,6,10,14,16-heptaene-4-carboxamide
CAS Number3036049-17-6
PubChem CID171391782
IUPAC Name(10Z)-N-[4-[2-(diethylamino)ethylcarbamoyl]cyclohexyl]-15-methyl-13-oxa-2,6,8,19-tetrazatricyclo[12.3.1.13,7]nonadeca-1(18),3(19),4,6,10,14,16-heptaene-4-carboxamide
Molecular FormulaC29H41N7O3
Molecular Weight535.7
XLogP3.6
Topological Polar Surface Area121
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count8
Rotatable Bond Count8
Heavy Atom Count39
Formal Charge0
Complexity800
SMILES
CCN(CC)CCNC(=O)C1CCC(CC1)NC(=O)C2=CN=C3NC/C=C\COC4=C(C=CC(=C4)NC2=N3)C
InChI
InChI=1S/C29H41N7O3/c1-4-36(5-2)16-15-30-27(37)21-9-12-22(13-10-21)34-28(38)24-19-32-29-31-14-6-7-17-39-25-18-23(11-8-20(25)3)33-26(24)35-29/h6-8,11,18-19,21-22H,4-5,9-10,12-17H2,1-3H3,(H,30,37)(H,34,38)(H2,31,32,33,35)/b7-6-
InChIKey
UEMPFKOYBHCUIG-SREVYHEPSA-N
Chemical Structure
2D Structure
2D structure of (10Z)-N-[4-[2-(diethylamino)ethylcarbamoyl]cyclohexyl]-15-methyl-13-oxa-2,6,8,19-tetrazatricyclo[12.3.1.13,7]nonadeca-1(18),3(19),4,6,10,14,16-heptaene-4-carboxamide
CAS: 3036049-17-6
CID: 171391782
Formula: C29H41N7O3
MW: 535.7
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight535.7
XLogP33.6
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count8
Rotatable Bond Count8
Exact Mass535.32708820
Monoisotopic Mass535.32708820
Topological Polar Surface Area121 Ų
Heavy Atom Count39
Formal Charge0
Complexity800
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19163236-01UNC1999
GTR19171507-01UNC1999
GTR19261982-01UNC8899
GTR19262115-01UNC8900
GTR19173608-01UNC569
GTR19159703-01UNC669

Alternative Products

CatalogName
T202988-01UNC8969

Popular Products