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D-DABA

CAT: 0804-HY-W291165Size: 1 EachDry Ice: NoHazardous: No
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Description
D-DABA is the enantiomeric form of L-DABA. D-DABA is also a weak inhibitor of GABA-T, but which has only one twentieth of the potency of the L-isomer in inhibiting GABA uptake.
CAS Number
26908-94-1
Product Name Alternative
D-2,4-Diaminobutyric acid
UNSPSC
12352211
Hazard Statement
H302-H315-H319-H335
Target
GABA Receptor
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Neurological Disease
Smiles
C(CN)[C@H](C(=O)O)N
Molecular Formula
C4H10N2O2
Molecular Weight
118.13
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Johnston GA, Twitchin B. Stereospecificity of 2,4-diaminobutyric acid with respect to inhibition of 4-aminobutyric acid uptake and binding. Br J Pharmacol. 1977 Jan;59 (1) :218-9. |[2]Taberner, P.V., Pycock, C.J. (1981) . The Effects of GABA Uptake Inhibitors including 2, 4-Diaminobutyric Acid on GABA Metabolism in vivo . In: Pycock, C.J., Taberner, P.V. (eds) Central Neurotransmitter Turnover. Springer, Boston, MA.
Shipping Conditions
Room temperature
Scientific Category
Reference compound2
Clinical Information
No Development Reported

Chemical Information

2,4-Diaminobutyric acid, D-

D-2,4-diaminobutyric acid is a 2,4-diaminobutyric acid that has R-configuration. It has a role as a bacterial metabolite. It is functionally related to a butyric acid. It is an enantiomer of a L-2,4-diaminobutyric acid.

CAS Number26908-94-1
PubChem CID638153
IUPAC Name(2R)-2,4-diaminobutanoic acid
Molecular FormulaC4H10N2O2
Molecular Weight118.13
XLogP-4.6
Topological Polar Surface Area89.3
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count4
Rotatable Bond Count3
Heavy Atom Count8
Formal Charge0
Complexity84
SMILES
C(CN)[C@H](C(=O)O)N
InChI
InChI=1S/C4H10N2O2/c5-2-1-3(6)4(7)8/h3H,1-2,5-6H2,(H,7,8)/t3-/m1/s1
InChIKey
OGNSCSPNOLGXSM-GSVOUGTGSA-N
Chemical Structure
2D Structure
2D structure of 2,4-Diaminobutyric acid, D-
CAS: 26908-94-1
CID: 638153
Formula: C4H10N2O2
MW: 118.13
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight118.13
XLogP3-4.6
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count4
Rotatable Bond Count3
Exact Mass118.074227566
Monoisotopic Mass118.074227566
Topological Polar Surface Area89.3 Ų
Heavy Atom Count8
Formal Charge0
Complexity84.1
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes