L-DABA (Standard)

• Description :

  L-DABA (Standard) is the analytical standard of L-DABA. This product is intended for research and analytical applications. L-DABA (L-2,4-Diaminobutyric acid) is a week GABA transaminase inhibitor with an IC50 of larger than 500 μM; exhibits antitumor activity in vivo and in vitro.

• Product Name Alternative :

  L-2,4-Diaminobutyric acid (Standard)

• UNSPSC :

  12352211

• Target :

  Endogenous Metabolite; GABA Receptor; Reference Standards

• Related Pathways :

  Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling; Others

• Field of Research :

  Neurological Disease; Cancer

• Smiles :

  O=C(O)[C@@H](N)CCN

• Molecular Formula :

  C4H10N2O2

• Molecular Weight :

  118.13

• References & Citations :

  [1]Ronquist G, et al. Antitumor activity of L-2,4 diaminobuturic acid against mouse fibrosarcoma cells in vitro and in vivo. J Cancer Res Clin Oncol. 1980;96 (3) :259-68.|[2]Beart PM, et al. l-2,4-Diaminobutyric acid and the GABA system. Neurosci Lett. 1977 Jul;5 (3-4) :193-8.|[3]Panasci L, et al. The cytolytic effect of L-2,4 diaminobutyric acid with malignant glioma cells and fibroblasts. Cancer Chemother Pharmacol. 1988;21 (2) :143-4.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference Standards

• CAS Number :

  [1758-80-1]