NP-184

• Description :

  NP-184 is a novel orally active antithrombotic agent. NP-184 selectively inhibits TXA2 synthase activity with an IC50 value of 4.3 μM. NP-184 has antiplatelet and antithrombotic activities. NP-184 can be used in the research of thromboembolic diseases[1].

• UNSPSC :

  12352005

• Hazard Statement :

  H302-H315-H319-H335

• Target :

  Prostaglandin Receptor

• Related Pathways :

  GPCR/G Protein

• Field of Research :

  Cardiovascular Disease

• Smiles :

  CC1=CC=C(C2=NC3=CC=CC=C3N2)O1

• Molecular Formula :

  C12H10N2O

• Molecular Weight :

  198.22

• Precautions :

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362-P403+P233-P405-P501

• References & Citations :

  [1]Kuo HL, et al. NP-184[2- (5-methyl-2-furyl) benzimidazole], a novel orally active antithrombotic agent with dual antiplatelet and anticoagulant activities. Naunyn Schmiedebergs Arch Pharmacol. 2010 Jun;381 (6) :495-505.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound2

• Clinical Information :

  No Development Reported

• CAS Number :

  [78706-11-3]