LP-184

• Description :

  LP-184 (compound 6), an acylfulvene analog, inhibits tumor growth. LP-184 has potent anti-cancer activity in the ovarian, colon, prostate and pancreatic cell lines. (patent WO2007019308A2) .

• UNSPSC :

  12352211

• Target :

  DNA Alkylator/Crosslinker; Drug Derivative

• Type :

  Reference compound

• Related Pathways :

  Cell Cycle/DNA Damage; Others

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/lp-184.html

• Purity :

  99.37

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  CC(C1(CC1)[C@@](O)(C2=O)C)=C3C2=CC(C)=C3CN(O)C(N)=O

• Molecular Formula :

  C16H20N2O4

• Molecular Weight :

  304.34

• References & Citations :

  [1]Trevor C. Mcmorris, et al. Illudin analogs useful as anticancer agents. WO2007019308A2.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 2

• CAS Number :

  [924835-67-6]