PF-184

• Target :

  I?B/IKK|||Others

• Related Pathways :

  NF-?B|||Others

• Bioactivity :

  PF-184 is a potent, selective inhibitor of IKK-2 with an IC50 value of 37 nM, demonstrating significant selectivity over rhIKK-1, IKKi, and over 30 other tyrosine and serine/threonine kinases. It is utilized in inflammation research, including studies on asthma and chronic obstructive pulmonary disease.

• Smiles :

  C[C@@]1([C@](C)(CN(C2=NC=C(Cl)C(C(NC(C=C3)=CC4=C3CCC(C(C(N)=O)=N5)=C4N5C6=CC=C(F)C=C6)=O)=C2)C1)CO)CO

• Molecular Formula :

  C32H32ClFN6O4

• Molecular Weight :

  619.09

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C