(E/Z) -Oleamide

• Description :

  (E/Z) -Oleamide (Octadec-9-enamide) is a PPARα ligand in hippocampal nuclei. (E/Z) -Oleamide can be isolated from plant Galium aparine L. (GA) . (E/Z) -Oleamide controls hippocampal plasticity via transcriptional activation of CREB, and regulates feeding and sexual behavior in rats[1][2][3].

• Product Name Alternative :

  Octadec-9-enamide

• UNSPSC :

  12352211

• Hazard Statement :

  H302-H315-H319-H335

• Target :

  PPAR

• Related Pathways :

  Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

• Field of Research :

  Neurological Disease

• Smiles :

  O=C(CCCCCCC/C=C/CCCCCCCC)N

• Molecular Formula :

  C18H35NO

• Molecular Weight :

  281.48

• Precautions :

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

• References & Citations :

  [1]Roy A, et al. Identification and characterization of PPARα ligands in the hippocampus. Nat Chem Biol. 2016 Dec;12 (12) :1075-1083. |[2]Sahin B, et al. Galium aparine L. protects against acetaminophen-induced hepatotoxicity in rats. Chem Biol Interact. 2022 Oct 1;366:110119. |[3]Martínez-González D, et al. Oleamide and anandamide effects on food intake and sexual behavior of rats. Neurosci Lett. 2004 Jun 24;364 (1) :1-6.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound2

• Clinical Information :

  No Development Reported

• Isoform :

  PPARα

• CAS Number :

  [3322-62-1]