PF-06688992

• Description:

  PF-06688992 is an antibody-drug conjugate (ADC) targeting the GD3 antigen, which is composed of humanized anti-GD3 huR24 linked to a chemotherapeutic agent. PF-06688992 can induce tumor cell apoptosis. PF-06688992 is promising for research of GD3-overexpressing tumors such as melanoma[1].

• UNSPSC:

  12352100

• Target:

  Antibody-Drug Conjugates (ADCs) ; Apoptosis

• Related Pathways:

  Antibody-drug Conjugate/ADC Related; Apoptosis

• Field of Research:

  Cancer

• References & Citations:

  [1]Berois N, et al. Targeting Tumor Glycans for Cancer Therapy: Successes, Limitations, and Perspectives. Cancers (Basel) . 2022 Jan 27;14 (3) :645.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Inhibitory Antibodies

• Clinical Information:

  No Development Reported