MK-4166

• Description :

  MK-4166 is a humanized IgG1 agonist monoclonal antibody targeting GITR. MK-4166 enhances the proliferation of both naïve and tumor-infiltrating T lymphocytes[1].

• UNSPSC :

  12352203

• Target :

  TNF Receptor

• Related Pathways :

  Apoptosis

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Purity :

  98.20

• Smiles :

  [MK-4166]

• Molecular Weight :

  (145.2 kDa)

• References & Citations :

  [1]Sukumar S, et al. Characterization of MK-4166, a Clinical Agonistic Antibody That Targets Human GITR and Inhibits the Generation and Suppressive Effects of T Regulatory Cells. Cancer Res. 2017;77 (16) :4378-4388.

• Shipping Conditions :

  Dry Ice

• Storage Conditions :

  -80°C

• Scientific Category :

  Inhibitory Antibodies

• Clinical Information :

  Phase 1