JKC 302

• Description :

  JKC 302 is an ET-A receptor antagonist. JKC 302 partly blocks ET-1-induced contraction in asthmatic rat trachea ring[1][2].

• UNSPSC :

  12352209

• Target :

  Endothelin Receptor

• Related Pathways :

  GPCR/G Protein

• Field of Research :

  Cardiovascular Disease

• Smiles :

  O=C(N[C@@H](C(N1[C@](CCC1)([H])C(N[C@@H](C(N[C@H](C(N2)=O)CC(C)C)=O)C(C)C)=O)=O)CO)[C@H]2CC3=CNC4=CC=CC=C34

• Molecular Formula :

  C30H42N6O6

• Molecular Weight :

  582.69

• References & Citations :

  [1]Basilico N, et al. The lipid moiety of haemozoin (Malaria Pigment) and P. falciparum parasitised red blood cells bind synthetic and native endothelin-1. J Biomed Biotechnol. 2010;2010:854927.|[2]Tiequn HUANG, et al. Role of endothelin and nitric oxide in the pathogenesis of asthma. Chinese Journal of Pathophysiology ; (12) : 435-437, 2001.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Peptides

• Clinical Information :

  No Development Reported

• CAS Number :

  [153982-38-8]