RU-302

CAT: 0804-HY-124066-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-124066-01Size:5 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
RU-302 is a pan TAM inhibitor that blocks the interface between the TAM Ig1 ectodomain and the Gas6 Lg domain. RU-302 effectively blocks Gas6-inducible Axl receptor activation with a low micromolar IC50in cell assays, and suppresses lung cancer tumor growth[1].
CAS Number
[1182129-77-6]
UNSPSC
12352005
Target
TAM Receptor
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ru-302.html
Purity
98.72
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=CC=C1SCC2=C(C)ON=C2C)N3CCN(C4=CC=CC(C(F)(F)F)=C4)CC3
Molecular Formula
C24H24F3N3O2S
Molecular Weight
475.53
References & Citations
[1]Kimani SG, et al. Small molecule inhibitors block Gas6-inducible TAM activation and tumorigenicity. Sci Rep. 2017 Mar 8;7:43908.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Axl

Related Products

CatalogName
HY-120240AND-302
HY-105412ARU 52583
HY-136628RU 25434
HY-136969RU 752
HY-114180-01RU.521
HY-121574RU 27849
HY-162045Ru-4T
HY-117984RU 35929
HY-117486RU 56187
HY-161668Ru-Poma

Alternative Products

CatalogName
MBS3615427-01RU-302
A19014-10RU-302 10mg
A19014-5RU-302 5mg
A19014-25RU-302 25mg
A19014-50RU-302 50mg
A19014-100RU-302 100mg
A19014-200RU-302 200mg
A19014-1RU-302 1mg
A19014-10mM-DRU-302 10mM * 1mL in DMSO
MBS5773503AND-302

Popular Products