KP-302
CAT:
804-HY-150307-04
Size:
10 mM / 1 mL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
KP-302
- CAS Number: 2082765-42-0
- UNSPSC Description: KP-302 (compound 23) is a selective inhibitor of protein arginine deaminase PAD2 with a Ki of 60 μM. KP-302 also reversed physical disability in the EAE mouse model of multiple sclerosis (MS) and eliminated T cell infiltration in the brain. KP-302 has the potential to be a disease-modifying agent for MS[1].
- Target Antigen: Protein Arginine Deiminase
- Type: Reference compound
- Related Pathways: Epigenetics
- Applications: COVID-19-immunoregulation
- Field of Research: Inflammation/Immunology
- Assay Protocol: https://www.medchemexpress.com/kp-302.html
- Solubility: DMSO : 100 mg/mL (ultrasonic)
- Smiles: O=C(C1=CC=CN1C)N[C@H](C(NCC2=CC=CC=C2)=O)CCN3C=CN=C3
- Molecular Weight: 365.43
- References & Citations: [1]Sarswat A, et al. Inhibitors of protein arginine deiminases and their efficacy in animal models of multiple sclerosis. Bioorg Med Chem. 2017 May 1;25(9):2643-2656.
- Shipping Conditions: Room Temperature
- Clinical Information: No Development Reported