NOTA-AUNP-12

CAT: 0804-HY-P11347Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-P11347Size:1 Each
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Description
NOTA-AUNP-12 is a PD-L1 antagonist (IC50=2.24x10−7 M) . NOTA-AUNP-12 is promising for research of cancers (e.g., lung/esophageal cancers) [1].
UNSPSC
12352209
Target
PD-1/PD-L1
Related Pathways
Immunology/Inflammation
Field of Research
Cancer
Smiles
OC(CC[C@@H](C(N)=O)NC([C@H](CCCCN)NC([C@H]([C@@H](C)CC)NC([C@H](CCC(N)=O)NC([C@H](C)NC([C@H](CCCCN)NC([C@H]1N(CCC1)C([C@H](C)NC([C@H](CC(C)C)NC([C@H](CCC(N)=O)NC([C@H]([C@H](O)C)NC([C@H](C(C)C)NC([C@H](CCCNC(N)=N)NC([C@@H](NC([C@H](CCCCNC([C@@H](NC([C@H](CO)NC([C@H](CCC(O)=O)NC([C@H](CO)NC([C@H]([C@H](O)C)NC([C@H](CC(N)=O)NC([C@@H](N)CO)=O)=O)=O)=O)=O)=O)CC2=CC=CC=C2)=O)NC([C@@H](NC([C@H](CO)NC([C@H](CCC(O)=O)NC([C@H](CO)NC([C@H]([C@H](O)C)NC([C@H](CC(N)=O)NC([C@H](CO)NC(CN3CCN(CC(O)=O)CCN(CC(O)=O)CC3)=O)=O)=O)=O)=O)=O)=O)CC4=CC=CC=C4)=O)=O)CC5=CC=CC=C5)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
Molecular Formula
C154H245N43O53
Molecular Weight
3546.85
References & Citations
[1]Zhou M, et al. [68Ga]Ga-AUNP-12 PET imaging to assess the PD-L1 status in preclinical and first-in-human study. Eur J Nucl Med Mol Imaging. 2024 Jan;51 (2) :369-379.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

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