NOTA

• UNSPSC Description:

  NOTA is a bifunctional chelate which acts as the framework to construct PET imaging tools. NOTA also can be used for probe design and signal amplification via the multivalent effect[1][2].

• Target Antigen:

  Radionuclide-Drug Conjugates (RDCs)

• Type:

  Reference compound

• Related Pathways:

  Antibody-drug Conjugate/ADC Related

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/nota.html

• Smiles:

  O=C(O)CN1CCN(CC(O)=O)CCN(CC(O)=O)CC1

• Molecular Weight:

  303.31

• References & Citations:

  [1]Singh AN, et al. Multivalent bifunctional chelator scaffolds for gallium-68 based positron emission tomography imaging probe design: signal amplification via multivalency. Bioconjug Chem. 2011;22(8):1650-1662. |[2]Liao AH, et al. Evaluation of 18F-labeled targeted perfluorocarbon-filled albumin microbubbles as a probe for microUS and microPET in tumor-bearing mice. Ultrasonics. 2013;53(2):320-327.

• Shipping Conditions:

  Blue Ice

• CAS Number:

  56491-86-2