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Caloxin 1b3

CAT: 0804-HY-P11292Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-P11292Size:1 Each
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Description
Caloxin 1b3, a peptide, is a selective plasma membrane Ca2+ pump 1 (PMCA1) inhibitor. Caloxin 1b3 significantly inhibits PMCA1 Ca2+–Mg2+-ATPase in the rabbit duodenal mucosa than the PMCA4 in the human erythrocyte ghosts. Caloxin 1b3 also increases cytosolic Ca2+ concentration in endothelial cells. Caloxin 1b3 can be used for cardiovascular disorders research[1].
UNSPSC
12352209
Target
Calcium Channel
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Cardiovascular Disease
Smiles
O=C(N[C@@H]([C@@H](C)CC)C(N1[C@@H](CCC1)C(N[C@@H](CCCCN)C(N[C@@H](CC2=CNC3=CC=CC=C23)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CO)C(N[C@@H]([C@@H](C)CC)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCC(N)=O)C(N[C@@H](C)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(NCC(NCC(NCC(N[C@@H](CO)C(N[C@@H](CCCCN)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H]([C@H](O)C)N
Molecular Formula
C88H150N26O22
Molecular Weight
1924.29
References & Citations
[1]Szewczyk MM, et al. Caloxin 1b3: a novel plasma membrane Ca (2+) -pump isoform 1 selective inhibitor that increases cytosolic Ca (2+) in endothelial cells. Cell Calcium. 2010 Dec;48 (6) :352-7.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

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