Hot

Calcein-AM

CAT: 0804-HY-D0041-01Size: 1 mgDry Ice: YesHazardous: No
CAT#:0804-HY-D0041-01Size:1 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Calcein AM, has cell membrane permeability and can easily enter the cell. Calcein AM has no fluorescence and is hydrolyzed by endogenous esterase in the cell to produce polar molecule Calcein (Calcein), which has strong negative charge and cannot permeate the cell membrane. Calcein can emit strong green fluorescence, so it is often used with Propidium Iodide for cell viability/virulence detection, excitation/emission wavelength: 494/515 nm[1].
CAS Number
[148504-34-1]
Product Name Alternative
Calcein acetoxymethyl ester
UNSPSC
12171500
Hazard Statement
H302
Target
Fluorescent Dye
Type
Dye Reagents
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Calcein-AM.html
Purity
99.73
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1OC2(C(C=C(CN(CC(OCOC(C)=O)=O)CC(OCOC(C)=O)=O)C(OC(C)=O)=C3)=C3OC4=CC(OC(C)=O)=C(CN(CC(OCOC(C)=O)=O)CC(OCOC(C)=O)=O)C=C24)C5=C1C=CC=C5
Molecular Formula
C46H46N2O23
Molecular Weight
994.86
Precautions
H302
References & Citations
[1]Wang XM, et al. A new microcellular cytotoxicity test based on calcein-AM release. Hum Immunol. 1993 Aug;37 (4) :264-70.|[2]Braut-Boucher F, et al. A non-isotopic, highly sensitive, fluorimetric, cell-cell adhesion microplate assay using calceinAM-labeled lymphocytes. J Immunol Methods. 1995 Jan 13;178 (1) :41-51.|[3]Bratosin D, et al. Novel fluorescence assay using calcein-AM for the determination of human erythrocyte viabilityand aging. Cytometry A. 2005 Jul;66 (1) :78-84.|[4]Holló Z, et al. Calcein accumulation as a fluorometric functional assay of the multidrug transporter. Biochim Biophys Acta. 1994 May 11;1191 (2) :384-8.
Shipping Conditions
Dry Ice
Storage Conditions
-80°C, protect from light, stored under nitrogen
Scientific Category
Dye Reagents
Clinical Information
No Development Reported

Related Products

CatalogName
HY-124298Calcein Blue AM
HY-D0040Calcein
HY-101887-01Calcein Blue
HY-W329161-01Calcein sodium salt
HY-D0830-01Calcein (tetraethyl ester)
HY-D1249-01Calcein (mixture of isomers)
HY-W419044ACalcein (calcium potassium)
HY-147367AM-1488
HY-13467-01AM-1638
HY-125967-01AM 374

Alternative Products

CatalogName
MBS9719178-01Calcein AM
MBS5755801Calcein-AM
E37F22002-1 mgCalcein, AM
E37F22002Calcein,-AM
B7755-1Calcein AM (Calcein acetoxymethyl ester)
B2011296Calcein Blue AM
21900-AATCalcein Red™ AM
21905-AATCalcein UltraGreen™ AM
354216Calcein AM 10x50ug

Popular Products