RegisterLogin

Calcein

CAT: 0804-HY-D0040Size: 100 mgDry Ice: NoHazardous: No
CAT#:0804-HY-D0040Size:100 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Calcein is a fluorescent dye and self-quenching probe, used as an indicator of lipid vesicle leakage, and also as a complexometric indicator for titration of calcium ions with EDTA, and for fluorometric determination of calcium. Calcein cannot directly cross the intact cell membrane of a living cell, unlike Calcein-AM (HY-D0041) which is cell-permeable. Calcein can also be used as a model drug for evaluating efficiency and bioavailability of drug delivery systems[1][2].
CAS Number
[1461-15-0]
Product Name Alternative
Fluorexon
UNSPSC
12171500
Hazard Statement
H302, H315, H319, H332, H335
Target
Fluorescent Dye
Type
Dye Reagents
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/Calcein.html
Solubility
1M NaOH : 50 mg/mL (ultrasonic) |DMSO : 2 mg/mL (ultrasonic) |H2O : 5.65 mg/mL (ultrasonic; warming; adjust pH to 8 with 1 M NaOH; heat to 60°C)
Smiles
O=C1OC2(C3=C(OC4=C2C=C(CN(CC(O)=O)CC(O)=O)C(O)=C4)C=C(O)C(CN(CC(O)=O)CC(O)=O)=C3)C5=C1C=CC=C5
Molecular Formula
C30H26N2O13
Molecular Weight
622.53
Precautions
H302, H315, H319, H332, H335
References & Citations
[1]Marques-Santos LF, et al. ABCB1 and ABCC1-like transporters in immune system cells from sea urchins Echinometra lucunter and Echinus esculentus and oysters Crassostrea gasar and Crassostrea gigas. Fish Shellfish Immunol. 2017 Sep 5;70:195-203.|[2]Maherani B, et al., Calcein release behavior from liposomal bilayer; influence of physicochemical/mechanical/structural properties of lipids. Biochimie. 2013 Nov;95 (11) :2018-33.|[3]Shao B, et al. Caffeic Acid Phenyl Ester (CAPE) Protects against Iron-Mediated Cellular DNA Damage through Its Strong Iron-Binding Ability and High Lipophilicity. Antioxidants (Basel) . 2021 May 18;10 (5) :798.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Dye Reagents
Clinical Information
No Development Reported

Related Products

CatalogName
HY-P10050-01Calpain substrate
HY-P11292Caloxin 1b3
HY-P3278-01Caloxin 2A1
HY-P5421-01Caloxin 1B1
HY-P5422Caloxin 3A1
HY-125592Calyxin H
HY-N3527Calyxin B
HY-P10655-01Caloxin 1C2
HY-148535Calpain Inhibitor XI
HY-P80578-01Calnexin Antibody (Rabbit)

Alternative Products

CatalogName
M22163-01Calcein
B7755-1Calcein AM (Calcein acetoxymethyl ester)
B2019146Calcein Blue
4892-010-01Calcein AM
E37F22002-1 mgCalcein, AM

Popular Products