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Caloxin 2A1

CAT: 0804-HY-P3278-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-P3278-01Size:5 mg
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Description
Caloxin 2A1 is an extracellular plasma membrane Ca2+-ATPase (PMCA) peptide inhibitor. Caloxin 2A1 does not affect basal Mg2+-ATPase or Na+-K+-ATPase[1].
CAS Number
[350670-85-8]
UNSPSC
12352209
Target
Proton Pump
Type
Peptides
Related Pathways
Membrane Transporter/Ion Channel
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/caloxin-2a1.html
Purity
99.86
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(N1[C@@H](CCC1)C(N[C@@H](CO)C(N[C@@H](CC2=CC=CC=C2)C(N3[C@@H](CCC3)C(N[C@@H](CO)C(N[C@@H](CO)C(NCC(NCC(NCC(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@@H](NC([C@H](CC(N)=O)NC([C@H](CO)NC([C@H](CC(N)=O)NC([C@H](CO)NC([C@@H](N)C(C)C)=O)=O)=O)=O)=O)CC4=CNC5=CC=CC=C45
Molecular Formula
C64H91N19O22
Molecular Weight
1478.52
References & Citations
[1]J Chaudhary, et al. Caloxin: a novel plasma membrane Ca2+ pump inhibitor. Am J Physiol Cell Physiol. 2001 Apr;280 (4) :C1027-30.|[2]Yi-fei Chen, et al. Plasma membrane Ca2+-ATPase regulates Ca2+ signaling and the proliferation of airway smooth muscle cells. Eur J Pharmacol. 2014 Oct 5;740:733-41.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported

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