LR-17

• Description :

  LR-17 (TLT-1 (94-110) ), a 17-aa peptide, is a TREM-1 inhibitor. LR-17 shows anti-inflammatory effects that can reduce the secretion of pro-inflammatory cytokines induced by Lipopolysaccharides (HY-D1056) (LPS) . LR-17 can be used for the study of sepsis[1].

• Product Name Alternative :

  TLT-1 (94-110)

• UNSPSC :

  12352209

• Target :

  TREM receptor

• Related Pathways :

  Immunology/Inflammation

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Purity :

  97.52

• Smiles :

  OC(C=C1)=CC=C1C[C@@H](C(NCC(N[C@@H](CS)C(N[C@@H](CCSC)C(N[C@@H](C(C)C)C(N[C@@H](CC(O)=O)C(NCC(N[C@@H](C)C(N[C@H](C(O)=O)CCCNC(N)=N)=O)=O)=O)=O)=O)=O)=O)=O)NC([C@H](CCC(O)=O)NC(CNC([C@H](C)NC([C@H](CC(O)=O)NC([C@H](CCC(O)=O)NC([C@H](CCC(O)=O)NC([C@H](CCC(N)=O)NC([C@@H](N)CC(C)C)=O)=O)=O)=O)=O)=O)=O)=O

• Molecular Formula :

  C74H115N21O30S2

• Molecular Weight :

  1842.96

• References & Citations :

  [1]Siskind S, et al. TREM-1 Modulation Strategies for Sepsis. Front Immunol. 2022 Jun 15;13:907387. doi: 10.3389/fimmu.2022.907387.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

• Scientific Category :

  Peptides

• Clinical Information :

  No Development Reported

• CAS Number :

  [1256099-50-9]