[D-Asp3]-Microcystin-LR

[D-Asp3]-Microcystin-LR

• CAS Number: 120011-66-7
• UNSPSC Description: Microcystin-[D-Asp3]-LR/Microcystin A is a cyanotoxin. Microcystin-[D-Asp3]-LR/Microcystin A can activate Nrf2 and promote oxidative stress response. Microcystin-[D-Asp3]-LR/Microcystin A can also be used in toxicology research[1][2].
• Target Antigen: Keap1-Nrf2
• Type: Peptides
• Related Pathways: NF-κB
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology
• Solubility: 10 mM in DMSO
• Smiles: CO[C@@H](CC1=CC=CC=C1)[C@@H](C)/C=C(C)/C=C/[C@@H]2NC([C@@H](NC(C[C@@H](NC([C@@H](NC([C@H](NC(C(N(C(CC[C@@H](NC([C@H]2C)=O)C(O)=O)=O)C)=C)=O)C)=O)CC(C)C)=O)C(O)=O)=O)CCCNC(N)=N)=O
• Molecular Weight: 981.15
• References & Citations: [1]Arman T, et al. Microcystin Toxicokinetics, Molecular Toxicology, and Pathophysiology in Preclinical Rodent Models and Humans. Toxins (Basel). 2021 Jul 29;13(8):537. |[2]Lundqvist J, et al. Microcystins activate nuclear factor erythroid 2-related factor 2 (Nrf2) in human liver cells in vitro - Implications for an oxidative stress induction by microcystins. Toxicon. 2017 Feb;126:47-50.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported