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Microcystin-LR

CAT: 0804-HY-P0072-01Size: 50 µgDry Ice: NoHazardous: No
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CAT#:0804-HY-P0072-01Size:50 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
101043-37-2
UNSPSC Description
Microcystin-LR is a potent inhibitor of type 1 and type 2A protein phosphatases (PP1 and PP2A), with IC50s of 1.7 nM and 0.04 nM, respectively.
Target Antigen
Phosphatase
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Purity
99.0
Solubility
Ethanol : 0.5 mg/mL (ultrasonic)
Smiles
CC(/C=C/[C@@H]([C@@H](C(N[C@H](CCC(N(C(C(N[C@@H]1C)=O)=C)C)=O)C(O)=O)=O)C)NC([C@@H](NC([C@H]([C@@H](NC([C@](NC1=O)([H])CC(C)C)=O)C(O)=O)C)=O)CCCNC(N)=N)=O)=C\[C@H](C)[C@@H](OC)CC2=CC=CC=C2
Molecular Weight
995.17
References & Citations
[1]Honkanen RE, et al. Characterization of microcystin-LR, a potent inhibitor of type 1 and type 2A protein phosphatases. J Biol Chem. 1990 Nov 15;265(32):19401-4.|[2]Lone Y, et al. Microcystin-LR Induced Immunotoxicity in Mammals. J Toxicol. 2016:8048125.
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, 2 years
Clinical Information
No Development Reported

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