Mp-4D7-pF2

• Description :

  Mp-4D7-pF2, a cell-penetrating bicyclic peptide, is a noncovalent SARS-CoV-2 main protease inhibitor with an IC50 of 4.51 μM. Mp-4D7-pF2 has an antiviral activity against SARS-CoV-2 with no cytotoxicity. Mp-4D7-pF2 can used for COVID-19 infections research[1].

• UNSPSC :

  12352209

• Target :

  SARS-CoV; Virus Protease

• Related Pathways :

  Anti-infection

• Field of Research :

  Infection

• Smiles :

  O=C(N[C@@H](C(C)C)C(N[C@@H](CSC1=C(F)C(F)=C2C(F)=C1F)C(N[C@H](CC3=CC=CC=C3)C(N[C@@H](CC4=CNC=N4)C(N[C@@H]([C@H](O)C)C(N[C@@H]([C@H](O)C)C(N[C@@H]([C@H](O)C)C(N5[C@@H](CCC5)C(N[C@@H](CC6=CC=CC=C6)C(N[C@@H](CSC7=C(F)C(F)=C2C(F)=C7F)C(N8[C@@H](CCC8)C(N9[C@@H](CCC9)C(N[C@H](CC%10)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)C(CC%11=CC=C(C=C%11)O)NC%10=O

• Molecular Formula :

  C88H101F8N17O19S2

• Molecular Weight :

  1916.96

• References & Citations :

  [1]Tan Y, et al. De Novo Discovery of a Noncovalent Cell-Penetrating Bicyclic Peptide Inhibitor Targeting SARS-CoV-2 Main Protease. J Med Chem. 2024 Nov 28;67 (22) :20258-20274.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Peptides

• Clinical Information :

  No Development Reported