XMU-MP-3
CAT:
804-HY-136531-02
Size:
50 mg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
XMU-MP-3
- CAS Number: 2031152-08-4
- UNSPSC Description: XMU-MP-3 is a potent non-covalent BTK inhibitor with IC50s of 10.7 nM and 17.0 nM for BTK WT and BTK C481S mutation in the presence of 10 μM ATP, respectively. XMU-MP-3 also induces apoptosis[1].
- Target Antigen: Apoptosis; Btk
- Type: Reference compound
- Related Pathways: Apoptosis;Protein Tyrosine Kinase/RTK
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/xmu-mp-3.html
- Smiles: O=C(NC1=CC=C(C)C(N2CC3=CN=C(NC4=CC(C)=NN4C)N=C3N(C)C2)=C1)C5=CC=CC(C(F)(F)F)=C5
- Molecular Weight: 536.55
- References & Citations: [1]Fu Gui, et al. A Non-Covalent Inhibitor XMU-MP-3 Overrides Ibrutinib-Resistant Btk C481S Mutation in B-cell Malignancies. Br J Pharmacol. 2019 Dec;176(23):4491-4509.
- Shipping Conditions: Room Temperature