MP-010

• Description:

  MP-010 is a FKBP12 ligand that regulates cytosolic calcium by stabilizing RyR channel activity. MP-010 promotes functional improvement in SOD1G93A amyotrophic lateral sclerosis (ALS) mice, as evidenced by improved motor coordination, increased integrity of neuromuscular junctions, and significantly enhanced survival of spinal motor neurons. MP-010 can be used for research in the field of neurological diseases[1].

• UNSPSC:

  12352005

• Target:

  Calcium Channel; FKBP

• Related Pathways:

  Apoptosis; Autophagy; Cell Cycle/DNA Damage; Immunology/Inflammation; Membrane Transporter/Ion Channel; Neuronal Signaling

• Applications:

  Neuroscience-Neurodegeneration

• Field of Research:

  Neurological Disease

• Smiles:

  CN (C) CCN1N=NC (CS (C2=CC=C (OC) C=C2) =O) =C1

• Molecular Formula:

  C14H20N4O2S

• Molecular Weight:

  308.40

• References & Citations:

  [1]Moreno-Martinez L, et al. Novel FKBP prolyl isomerase 1A (FKBP12) ligand promotes functional improvement in SOD1G93A amyotrophic lateral sclerosis (ALS) mice. Br J Pharmacol. 2025 Feb 13.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  FKBP12

• CAS Number:

  3024617-59-9