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MP-010

CAT: 0804-HY-172152Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-172152Size:1 Each
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Description
MP-010 is a FKBP12 ligand that regulates cytosolic calcium by stabilizing RyR channel activity. MP-010 promotes functional improvement in SOD1G93A amyotrophic lateral sclerosis (ALS) mice, as evidenced by improved motor coordination, increased integrity of neuromuscular junctions, and significantly enhanced survival of spinal motor neurons. MP-010 can be used for research in the field of neurological diseases[1].
CAS Number
[3024617-59-9]
UNSPSC
12352005
Target
Calcium Channel; FKBP
Related Pathways
Apoptosis; Autophagy; Cell Cycle/DNA Damage; Immunology/Inflammation; Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Smiles
CN(C)CCN1N=NC(CS(C2=CC=C(OC)C=C2)=O)=C1
Molecular Formula
C14H20N4O2S
Molecular Weight
308.40
References & Citations
[1]Moreno-Martinez L, et al. Novel FKBP prolyl isomerase 1A (FKBP12) ligand promotes functional improvement in SOD1G93A amyotrophic lateral sclerosis (ALS) mice. Br J Pharmacol. 2025 Feb 13.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
FKBP12

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