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CPN-351 (TFA)

CAT: 0804-HY-P10473A-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-P10473A-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CPN-351 TFA (compound 9a), a pentapeptide, is a selective antagonist of human NMUR1 with a pA2 of 7.35. The antagonistic effect of CPN-351 TFA on human NMUR1 is 10 times higher than that on NMUR2. CPN-351 TFA can be used in the study of inflammation[1]. X
UNSPSC
12352209
Target
Neuromedin U Receptor (NMUR)
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Purity
99.06
Smiles
CN([C@H](C(N[C@@](CC1=CC=CC=C1)(C(N[C@H](C(N2CCC[C@H]2C(N[C@H](C(N)=O)CCCNC(N)=N)=O)=O)CCCNC(N)=N)=O)C)=O)CC3=CNC4=C3C=CC=C4)C(CC5=CC=CS5)=O.OC(C(F)(F)F)=O.
Molecular Formula
C45H61N13O6S.xC2HF3O2
Molecular Weight
912.11 (free base)
References & Citations
[1]Takayama K, et al. Discovery of a Pentapeptide Antagonist to Human Neuromedin U Receptor 1. ACS Med Chem Lett. 2024 May 24;15 (6) :885-891.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
NMUR1

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