ER-Laurdan

• Description :

  ER-Laurdan, a derivative of Laurdan (HY-D0080), is a fluorescent probe. ER-Laurdan contains a pentafluorophenyl (PFP) group with a PEG10 linker; the PFP group reacts with thiols in unfolded proteins in the ER and the linker provides flexibility for the protein-bound probe to integrate into the membrane. ER-Laurdan can be used to the study of the endoplasmic reticulum[1].

• UNSPSC :

  12352005

• Target :

  Fluorescent Dye

• Related Pathways :

  Others

• Field of Research :

  Others

• Purity :

  99

• Smiles :

  O=C(C1=C(F)C(F)=C(F)C(F)=C1F)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CN(C)C2=CC=C3C(C=CC(C(CCCCCCCCCCC)=O)=C3)=C2)=O

• Molecular Formula :

  C54H80F5N3O13

• Molecular Weight :

  1074.22

• References & Citations :

  [1]Wong AM, et al. Organelle-targeted Laurdans measure heterogeneity in subcellular membranes and their responses to saturated lipid stress. bioRxiv [Preprint]. 2024 Apr 20:2024.04.16.589828. doi: 10.1101/2024.04.16.589828. Update in: ACS Chem Biol. 2024 Aug 16;19 (8) :1773-1785.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C (Powder, protect from light)

• Scientific Category :

  Dye Reagents

• Clinical Information :

  No Development Reported

• CAS Number :

  [3091879-77-2]