ER-Laurdan

• Description:

  ER-Laurdan, a derivative of Laurdan (HY-D0080), is a fluorescent probe. ER-Laurdan contains a pentafluorophenyl (PFP) group with a PEG10 linker; the PFP group reacts with thiols in unfolded proteins in the ER and the linker provides flexibility for the protein-bound probe to integrate into the membrane. ER-Laurdan can be used to the study of the endoplasmic reticulum[1].

• UNSPSC:

  12352005

• Target:

  Fluorescent Dye

• Related Pathways:

  Others

• Field of Research:

  Others

• Purity:

  99

• Smiles:

  O=C (C1=C (F) C (F) =C (F) C (F) =C1F) NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC (CN (C) C2=CC=C3C (C=CC (C (CCCCCCCCCCC) =O) =C3) =C2) =O

• Molecular Formula:

  C54H80F5N3O13

• Molecular Weight:

  1074.22

• References & Citations:

  [1]Wong AM, et al. Organelle-targeted Laurdans measure heterogeneity in subcellular membranes and their responses to saturated lipid stress. bioRxiv [Preprint]. 2024 Apr 20:2024.04.16.589828. doi: 10.1101/2024.04.16.589828. Update in: ACS Chem Biol. 2024 Aug 16;19 (8) :1773-1785.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, protect from light)

• Scientific Category:

  Dye Reagents

• Clinical Information:

  No Development Reported

• CAS Number:

  3091879-77-2