Golgi-P

• Description:

  Golgi-P is a near-infrared Golgi-targeted fluorescent probe specifically used for the detection of Golgi polarity in living cells and living tissues. Golgi-P exhibits a significant polarity-dependent spectral behavior, with its emission wavelength shifting redward with polarity (Ex/Em: 700 nm/780-825 nm) . Golgi-P achieves near-infrared fluorescence imaging directly in the brain tissue of depressed mice. Golgi-P combines polarity sensing with Golgi-targeting functionality, providing a new tool for the molecular diagnosis of depression[1].

• UNSPSC:

  12352005

• Target:

  Fluorescent Dye

• Related Pathways:

  Others

• Field of Research:

  Neurological Disease

• Smiles:

  CC1(C)C(C=CC=C2)=C2N(CCC(C[C@@](C(O)=O)([H])CS)=O)/C1=C/C=C3CCCC(/C=C/C4=[O+][B-](F)(OC(C5=CC=CC=C5)=C4)F)=C\3Cl

• Molecular Formula:

  C36H37BClF2NO5S

• Molecular Weight:

  680.01

• References & Citations:

  [1]Li P, et al. Golgi Apparatus Polarity Indicates Depression-Like Behaviors of Mice Using in Vivo Fluorescence Imaging. Anal Chem. 2019 Mar 5;91 (5) :3382-3388.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Dye Reagents

• Clinical Information:

  No Development Reported