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CP-464709

CAT: 0804-HY-19454Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-19454Size:1 Each
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Description
CP-464709 is a Ghrelin receptor agonist that can penetrate the blood-brain barrier. CP-464709 causes an increase in blood pressure by activating pre sympathetic neurons in the spinal cord. CP-464709 causes biphasic blood pressure response when administered intravenously, while intrathecal administration only causes pressor. CP-464709 can be used for research on cardiovascular conditions[1].
CAS Number
193272-70-7
UNSPSC
12352005
Target
GHSR
Related Pathways
GPCR/G Protein
Field of Research
Cardiovascular Disease
Smiles
CC(C)(N)C(N[C@H](COCC1=CC=C(F)C=C1F)C(N(C[C@]23CC4=NC=CC=C4)CCC2=NN(CC(F)(F)F)C3=O)=O)=O
Molecular Formula
C28H31F5N6O4
Molecular Weight
610.58
References & Citations
[1]Ferens DM, et al. Functional and in situ hybridization evidence that preganglionic sympathetic vasoconstrictor neurons express ghrelin receptors. Neuroscience. 2010 Mar 17;166 (2) :671-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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