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LTD4 antagonist 3

CAT: 0804-HY-19178Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-19178Size:1 Each
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Description
LTD4 antagonist 3 (FK011 hydrochloride) is a LTD4 antagonist. LTD4 antagonist 3 has agonistic activity for PPAR-γ, with a fold-increase of 1.50 at 1 μM and 2.35 at 10 μM. LTD4 antagonist 3 can be used of development of non-steroidal anti-inflammatory drugs (NSAIDs) [1].
CAS Number
149437-51-4
Product Name Alternative
FK011 (hydrochloride)
UNSPSC
12352005
Target
Leukotriene Receptor; PPAR
Related Pathways
Cell Cycle/DNA Damage; GPCR/G Protein; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
COVID-19-anti-virus
Field of Research
Inflammation/Immunology
Smiles
O=C(CC1=C(COC2=CC3=C(OC(C4=NC(C(C)(C)C)=CS4)=C3)C=C2)C=CC=C1)O.Cl
Molecular Formula
C24H24ClNO4S
Molecular Weight
457.97
References & Citations
[1]Kojo H, et al. Evaluation of human peroxisome proliferator-activated receptor (PPAR) subtype selectivity of a variety of anti-inflammatory drugs based on a novel assay for PPAR delta (beta) . J Pharmacol Sci. 2003 Nov;93 (3) :347-55.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
LTD4/CysLT1; PPARγ

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