LTD4 antagonist 2

• Target:

  Leukotriene Receptor

• Related Pathways:

  GPCR/G Protein

• Bioactivity:

  LTD4 antagonist 2 (compound 6) functions as a leukotriene D4 (LTD4) antagonist with an IC50 of 2.8 ?M for the cysteinyl leukotriene 1 receptor (CysLT1R) . Additionally, it acts as an agonist for the G protein-coupled bile acid receptor 1 (GPBAR1), making it applicable for research into colitis, metabolic syndrome, and other GPBAR1- and CysLT1R-related diseases.

• Smiles:

  O=C(O)C=1C=CC=C(OCC2=NC=3C=CC=CC3C=C2)C1

• Molecular Formula:

  C17H13NO3

• Molecular Weight:

  279.29

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  107813-86-5