KRN-2391

CAT: 0804-HY-19116Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-19116Size:1 Each
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
KRN-2391 is a KATP channel opener with NO donor properties. KRN-2391 exerts dual inhibitory effects on overactive bladder (OAB) by activating KATP channels (causing cellular hyperpolarization and bladder smooth muscle relaxation) and releasing NO (enhancing relaxation via cGMP pathways) . KRN-2391 is promising for research of OAB[1].
CAS Number
[134431-49-5]
UNSPSC
12352005
Target
Potassium Channel
Related Pathways
Membrane Transporter/Ion Channel
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Neurological Disease
Smiles
O=[N+](OCC/N=C(C1=CC=CN=C1)/NC#N)[O-].CS(=O)(O)=O
Molecular Formula
C10H13N5O6S
Molecular Weight
331.31
References & Citations
[1]Kamiyama Y, et al. Inhibitory effects of nicorandil, a K ATP channel opener and a nitric oxide donor, on overactive bladder in animal models. BJU Int. 2008 Feb;101 (3) :360-5.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2

Related Products

CatalogName
HY-P990611KRN-330
HY-12060-01KRN-633
HY-12060R-01KRN-633 (Standard)
HY-112126-01KRN5
HY-112125-01KRN2
HY-112125A-01KRN2 (bromide)
HY-100221-01AM-2394
HY-148258-01GDC-2394
HY-136174-01RBN-2397
HY-150743-01ODN 2395

Alternative Products

CatalogName
T6137-01KRN-633
E1KS1557KRN 633
MBS5777449KRN 5500
T202861-01KRN-8602
A10504-2KRN 633 2mg
A10504-5KRN 633 5mg
A10504-100KRN 633 100mg
A10504-200KRN 633 200mg
A10504-10KRN 633 10mg
A10504-25KRN 633 25mg

Popular Products