Products for Research Use Only

KRN-633 (Standard)

CAT: 0804-HY-12060R-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-12060R-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
KRN-633 (Standard) is the analytical standard of KRN-633. This product is intended for research and analytical applications. KRN-633 is a potent VEGFR inhibitor with IC50s of 170, 160 and 125 nM for VEGFR1, VEGFR2 and VEGFR3, respectively.
CAS Number
286370-15-8
UNSPSC
12352100
Target
Reference Standards; VEGFR
Related Pathways
Others; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
ClC1=CC(OC2=NC=NC3=CC(OC)=C(C=C32)OC)=CC=C1NC(NCCC)=O
Molecular Formula
C20H21ClN4O4
Molecular Weight
416.86
References & Citations
[1]Nakamura K, et al. KRN633: A selective inhibitor of vascular endothelial growth factor receptor-2 tyrosine kinase that suppresses tumor angiogenesis and growth. Mol Cancer Ther. 2004 Dec;3 (12) :1639-49.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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