CGP-6809

• Description :

  CGP-6809 is an orally active DNA inhibitor. CGP-6809 exhibits antitumor activity against various transplantable tumors in mice and rats, including melanoma, prostate cancer, and rectal cancer. CGP-6809 can be used in research on various cancers, including melanoma, prostate cancer, and rectal cancer[1][2].

• CAS Number :

  [70457-70-4]

• UNSPSC :

  12352005

• Target :

  DNA/RNA Synthesis

• Related Pathways :

  Cell Cycle/DNA Damage

• Field of Research :

  Cancer

• Smiles :

  O=NN(C)C(NC[C@H]([C@]1([H])[C@@H]([C@H]([C@H](O1)OCC)O)OC)OC)=O

• Molecular Formula :

  C12H23N3O7

• Molecular Weight :

  321.33

• References & Citations :

  [1]Schieweck K, et al. CGP 6809, a sugar-containing nitrosourea derivative: pharmacological and physicochemical properties. Cancer Chemother Pharmacol. 1989;23 (6) :341-7. |[2]Fiebig HH, et al. CGP 6809--a new nitrosoureido-sugar derivative with activity in human tumor xenografts. Cancer Chemother Pharmacol. 1989;23 (6) :337-40.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported