MI-30

• Description:

  MI-30 is an orally active SARS-CoV-2 3CLpro inhibitor (IC50 = 17.2 nM) . MI-30 reduces viral load and lung lesions in a mouse model of SARS-CoV-2 infection. MI-30 may be used in coronavirus infection research[1].

• UNSPSC:

  12352005

• Target:

  SARS-CoV

• Related Pathways:

  Anti-infection

• Field of Research:

  Infection

• Smiles:

  O=C (NCC1) [C@@H]1C[C@@H] (C=O) NC ([C@@H]2[C@]3 ([H]) [C@] (CCC3) ([H]) CN2C (COC4=C (C=C (C=C4) Cl) Cl) =O) =O

• Molecular Formula:

  C23H27Cl2N3O5

• Molecular Weight:

  496.38

• References & Citations:

  [1]Qiao J, et al. SARS-CoV-2 Mpro inhibitors with antiviral activity in a transgenic mouse model. Science. 2021 Mar 26;371 (6536) :1374-1378.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  2698348-97-7