PSB-17365

• Description:

  PSB-17365 is a potent GPR84 agonist with EC50 values of 2.5 nM and 100 nM in a cAMP accumulation assay and a β-arrestin 2 recruitment assay, respectively[1].

• UNSPSC:

  12352005

• Target:

  GPR84

• Related Pathways:

  GPCR/G Protein

• Field of Research:

  Inflammation/Immunology

• Smiles:

  O=C1C=C(NCCC2=CC=C(C=C2)Br)NC(N1)=O

• Molecular Formula:

  C12H12BrN3O2

• Molecular Weight:

  310.15

• References & Citations:

  [1]Pillaiyar, T., et al., (2018) . 6- (Ar) Alkylamino-Substituted Uracil Derivatives: Lipid Mimetics with Potent Activity at the Orphan G Protein-Coupled Receptor 84 (GPR84) . ACS omega, 3 (3), 3365-3383.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [2189700-03-4]