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PSB-17365

CAT: 0931-T69824-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T69824-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2189700-03-4
Target
Others
Related Pathways
Others
Bioactivity
PSB-17365 is a potent GPR84 agonist. PSB-17365 exhibits EC50 values vs. GPR84 of 2.5nM in a cAMP accumulation assay, and 100nM in a β-arrestin 2 recruitment assay. No direct binding affinities are provided. PSB-17365 is selective for GPR84 compared to other free fatty acid receptors (FFAR1 and FFAR4) . GPR84, a Gi protein-coupled receptor that is activated by medium-chain (hydroxy) fatty acids, appears to play an important role in inflammation, immunity, and cancer.
Smiles
N(CCC1=CC=C(Br)C=C1)C2=CC(=O)NC(=O)N2
Molecular Formula
C12H12BrN3O2
Molecular Weight
310.15
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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