PSB-17365

• Target:

  Others

• Related Pathways:

  Others

• Bioactivity:

  PSB-17365 is a potent GPR84 agonist. PSB-17365 exhibits EC50 values vs. GPR84 of 2.5nM in a cAMP accumulation assay, and 100nM in a ?-arrestin 2 recruitment assay. No direct binding affinities are provided. PSB-17365 is selective for GPR84 compared to other free fatty acid receptors (FFAR1 and FFAR4) . GPR84, a Gi protein-coupled receptor that is activated by medium-chain (hydroxy) fatty acids, appears to play an important role in inflammation, immunity, and cancer.

• Smiles:

  N (CCC1=CC=C (Br) C=C1) C2=CC (=O) NC (=O) N2

• Molecular Formula:

  C12H12BrN3O2

• Molecular Weight:

  310.15

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2189700-03-4