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Nav1.7-IN-20

CAT: 0804-HY-179445Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-179445Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Nav1.7-IN-20 (Compound 3AG) is an orally active Nav1.7 channel inhibitor with an IC50 of 3.1 μM. Nav1.7-IN-20 demonstrates analgesic efficacy in a Complete Freund's adjuvant (CFA) inflammatory pain model. Nav1.7-IN-20 can be used for pain research[1].
UNSPSC
12352005
Target
Sodium Channel
Related Pathways
Membrane Transporter/Ion Channel
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Smiles
O=C(N1CCCCC1)/C=C/C=C/C2=CC(OCC3=CC=CC=C3Br)=C(OCC4=C(Br)C=CC=C4)C=C2
Molecular Formula
C30H29Br2NO3
Molecular Weight
611.36
References & Citations
[1]Vikram VN, et al. Discovery of O-alkylated derivative of piperine as Nav1.7 channel inhibitor for the treatment of pain. Bioorg Med Chem Lett. 2026 Feb 1;131:130461.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Nav1.7

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